Isolation of Enzymatically Active Replication Complexes from Feline Calicivirus-Infected Cells

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Isolation of enzymatically active replication complexes from feline calicivirus-infected cells.

A membranous fraction that could synthesize viral RNA in vitro in the presence of magnesium salt, ribonucleotides, and an ATP-regenerating system was isolated from feline calicivirus (FCV)-infected cells. The enzymatically active component of this fraction was designated FCV replication complexes (RCs), by analogy to other positive-strand RNA viruses. The newly synthesized RNA was characterized...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2002

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.76.17.8582-8595.2002